NP Workshop Study Guide - Preventive Care

The Comprehensive Exam at 65

One visit, two patients. What is shared, what differs for a 65-year-old male and a 65-year-old female, which screenings start, continue, or stop, and exactly which vaccines are due. Built from the current CDC Adult Immunization Schedule (2025, with the April 2025 RSV update) and current USPSTF A and B recommendations.

Age 65 - both sexesScreenings with ages + intervalsVaccines with dose + timingCases + quiz + cheat sheet
How to use this in workshop: Start with the shared core, then run the side-by-side. Most exam questions do not test whether you know a screening exists. They test the age window, the interval, the risk qualifier, and whether it should have stopped. Those details are spelled out in every table below.

1. The shared core exam at 65

The same skeleton applies to both patients. Sex-specific items layer on top in Sections 3 and 4.

Visit flow - in order

  1. Pre-visit chart review: prior screenings and dates, vaccine record, last colonoscopy, mammogram or PSA discussion, smoking pack-years, alcohol use, family history, advance directive on file.
  2. History of present concerns + interval history: new symptoms, hospitalizations, falls, weight change, sleep, pain, urinary and bowel changes, sexual health.
  3. Full medication reconciliation: prescriptions, OTCs, supplements, and borrowed meds. See Beers-type review below.
  4. Past medical, surgical, family, and social history update: occupation, living situation, food and housing security, transportation, health literacy, support system. These are the social drivers that change the plan.
  5. Review of systems: complete, with emphasis at 65 on vision, hearing, continence, cognition, mood, and gait.
  6. Vital signs and measures: BP in both arms if new hypertension is suspected, heart rate, respirations, temperature, height, weight, BMI, waist circumference, pain, oxygen saturation if indicated.
  7. Functional and safety assessment: ADLs, IADLs, Timed Up and Go or gait observation, home safety, driving safety, fall history in the last year.
  8. Physical exam, labs, screening orders, vaccines, counseling, and a written prevention plan with dates for everything due next.

Medication review - Beers-type high-risk meds

Flag, do not just list. The AGS Beers Criteria identify medications whose risks often outweigh benefits in older adults.

  • Anticholinergics: diphenhydramine, oxybutynin, TCAs. Risk: confusion, dry mouth, constipation, urinary retention, falls.
  • Benzodiazepines and Z-drugs: lorazepam, alprazolam, zolpidem. Risk: falls, fractures, cognitive impairment. Avoid for insomnia or agitation.
  • NSAIDs, especially chronic: ibuprofen, naproxen. Risk: GI bleed, kidney injury, BP rise. Risk jumps with anticoagulants, SSRIs, or steroids.
  • Sulfonylureas with long action: glyburide. Risk: prolonged hypoglycemia. Prefer safer diabetes agents.
  • Muscle relaxants, meperidine, sliding-scale insulin alone, and antipsychotics in dementia without a clear indication.
  • Deprescribing question for every med: What is it for, is it still needed, is the dose right for kidney function and age, and what interacts?

Cognition, mood, falls, function

  • Cognition: screen when there is concern from patient, family, or clinician. Tools: Mini-Cog, MoCA, MMSE. Medicare Annual Wellness Visit requires a cognition check. Also review delirium risk, sleep, and meds before labeling dementia.
  • Depression: USPSTF Grade B, screen adults including older adults. PHQ-2, then PHQ-9 if positive, with adequate follow-up systems in place.
  • Anxiety: USPSTF Grade B is for adults 64 and younger. At 65, screen on clinical judgment, not as a USPSTF B mandate. A classic trap.
  • Falls: ask about falls, steadiness, and fear of falling. USPSTF Grade B: exercise interventions for community-dwelling adults 65 and older at increased risk. Vitamin D for fall prevention is Grade D, do not recommend it for that purpose.
  • Hearing and vision: ask, whisper test or audiology referral, eye exam every 1 to 2 years. USPSTF gives hearing and vision screening in asymptomatic older adults an I statement, so test when there are symptoms or concerns.
  • Continence, nutrition, oral health, elder mistreatment risk, and advance care planning at every comprehensive visit at this age.

System-by-system physical exam checklist

  • General: appearance, distress, hygiene, affect
  • HEENT: visual acuity, pupils, extraocular movements, oral cavity and dentition, thyroid palpation, lymph nodes, hearing screen
  • Neck: carotid bruits, JVP, thyromegaly
  • Cardiovascular: rhythm, murmurs (aortic stenosis rises with age), pulses including pedal, edema
  • Lungs: effort, breath sounds, wheeze or crackles, smoking-related signs
  • Abdomen: tenderness, masses, liver span, aortic pulsation, bowel sounds
  • Musculoskeletal: gait, strength, joint range, kyphosis, foot exam
  • Neurologic: cranial nerves, strength, sensation, reflexes, coordination, gait and balance
  • Skin: full inspection, sun-exposed lesions, pressure areas, suspicious moles using ABCDE
  • Breast: see female and male notes in Sections 3 and 4
  • Genitourinary / pelvic / prostate: only as indicated and consented, see sex-specific sections
  • Rectal: not a screening test for colorectal or prostate cancer. Do for symptoms, bleeding, or anemia workup
  • Peripheral vascular: pulses, skin changes, ulcers. Ankle-brachial index only if symptomatic or high risk, USPSTF gives asymptomatic screening an I statement
  • Lymphatic and functional: nodes, plus observed sit-to-stand and walking

Routine labs - and why each is ordered

There is no single mandatory panel for a healthy 65-year-old. Order for screening indications below, not by habit. Workshop cases penalize shotgun panels.

TestWhy at 65Notes
Lipid panelCardiovascular risk and statin decisionUSPSTF statin Grade B: age 40 to 75 with 1 or more CV risk factors and 10-year risk 10% or higher. Grade C at 7.5 to 10%. I statement over 76.
A1C or fasting glucosePrediabetes and type 2 diabetes screeningUSPSTF Grade B: age 35 to 70 with overweight or obesity, every 3 years. At 65 it applies if BMI criteria met. Continue on clinical judgment after 70.
CBCOnly if indicatedFatigue, bleeding, pallor, before procedures. Not a USPSTF routine screen in asymptomatic adults.
CMP, kidney function, electrolytesMed safety, hypertension, diabetes, diuretic or ACE inhibitor useNeeded for prescribing and Beers review, not as a stand-alone screen.
TSHOnly if indicatedSymptoms, atrial fibrillation, amiodarone or lithium use. USPSTF: I statement for asymptomatic thyroid dysfunction.
Vitamin D, B12Only if indicatedDeficiency risk, metformin use, anemia, neuropathy, malabsorption. USPSTF: I statement for routine vitamin D screening in asymptomatic adults.
Hepatitis C antibody (one time)Universal adult screeningUSPSTF Grade B: all adults 18 to 79, once. Confirm with HCV RNA if positive.
HIV testAt least once in a lifetime screeningUSPSTF Grade A: age 15 to 65. At exactly 65, offer if never tested. Over 65, test if at increased risk.
UrinalysisOnly for symptomsDo not screen for asymptomatic bacteriuria in nonpregnant adults. USPSTF Grade D.

2. Side by side - what differs

Everything in this table is different by sex. Everything not listed here is shared, and lives in Sections 1 and 5.

Item65-year-old male65-year-old female
Abdominal aortic aneurysmOrder once One-time ultrasound, age 65 to 75, if he has EVER smoked. Grade B.Do not order routinely Never smoked: Grade D. Ever smoked or family history: selective, Grade C.
Prostate / cervicalPSA only with shared decision making. Grade C was 55 to 69, so at 65 it is a conversation, not an order. Grade D at 70 and older.Cervical screening STOPS at 65 if adequate prior screening and no high-risk history. See stopping rules in Section 4.
Breast screeningNo routine mammography. Evaluate any lump, nipple discharge, or gynecomastia.Biennial mammography, age 40 to 74, Grade B. At 65 she is squarely in the window.
Bone densityUSPSTF I statement. Test if risk factors, fragility fracture, steroids, low body weight, or clinical concern.Order at 65 DEXA for all women 65 and older, Grade B. Also younger postmenopausal women at increased risk.
Genital examTesticular and penile exam for symptoms, masses, lesions, discharge, or STI risk. No routine testicular cancer screening, Grade D.Pelvic exam only for symptoms or procedures. No screening pelvic exam benefit in asymptomatic nonpregnant adults. Breast exam is not a substitute for mammography.
Sexual health flagErectile dysfunction: ask directly. Treat it as a cardiovascular risk marker, review meds, glucose, lipids, BP, and smoking.Ask about libido, dyspareunia, vaginal dryness, postmenopausal bleeding. ANY postmenopausal bleeding needs prompt evaluation.
Osteoporosis risk medsReview steroids, alcohol, smoking, falls.Same, plus estrogen loss, prior fracture, parental hip fracture. Start calcium, vitamin D for deficiency, weight-bearing exercise, and pharmacotherapy if T-score -2.5 or lower or FRAX thresholds met.
VaccinesIdentical for a healthy male and female at 65. No sex difference in the Section 6 schedule. Differences only come from risk conditions, not sex.

3. Male-specific at 65

Four items account for almost every male case question at this age.

Prostate screening - shared decision making

  • USPSTF: Age 55 to 69, Grade C, individual decision. Age 70 and older, Grade D, do not screen.
  • At 65, the visit must include the talk: potential benefit is a small reduction in metastatic disease and prostate cancer death. Harms are false positives, biopsy complications, overdiagnosis, incontinence and erectile dysfunction from treatment.
  • If he chooses testing: PSA alone. Digital rectal exam is not a recommended screening test on its own.
  • Document that the discussion happened, his values, and his decision. Workshop graders look for that note.
  • Red flags that are not screening: urinary obstruction, hematuria, bone pain, weight loss. Those need diagnostic workup regardless of age.

AAA - the one-time ultrasound

  • Who: Men age 65 to 75 who have ever smoked, even 100 cigarettes in a lifetime counts as ever smoked in this definition.
  • What: One-time abdominal ultrasound. Grade B.
  • Men 65 to 75 who never smoked: Grade C, selectively offer based on family history and risk.
  • If AAA found: size drives surveillance intervals and vascular referral. Smoking cessation is part of treatment.

Testicular, penile, and ED notes

  • Testicular: no routine screening in asymptomatic adolescents or adults, Grade D. Exam for a lump, pain, swelling, or trauma.
  • Penile: inspect for lesions, phimosis, discharge, or STI signs when symptomatic or at risk.
  • Erectile dysfunction: ask, do not wait for him to raise it. ED predicts cardiovascular disease. Check BP, A1C, lipids, testosterone only if indicated, and review nitrates before any PDE5 inhibitor, plus Beers and antihypertensive meds.

4. Female-specific at 65

Three of these are continuation or stopping decisions, not new starts. That is why they are tested so heavily.

Mammography and cervical - one continues, one stops

  • Mammography: Biennial (every 2 years), age 40 to 74, Grade B. At 65, order it if she is not up to date. Age 75 and older: I statement, insufficient evidence, individualize by health and life expectancy.
  • Cervical screening stops at 65 when ALL are true: adequate prior screening, no history of CIN 2 or higher in the last 20 years, and not otherwise at high risk (immunocompromised, DES exposure, prior cervical cancer).
  • Adequate prior screening means: 3 consecutive negative cytology results OR 2 consecutive negative high-risk HPV based tests (HPV alone or co-test) within the previous 10 years, with the most recent test within 5 years.
  • If she has had a hysterectomy with removal of the cervix and no history of high-grade lesion or cervical cancer: do not screen. Grade D.
  • If she was never screened or screening is inadequate: keep screening at 65 until criteria are met. Never-screened is the exception case workshops love.

Osteoporosis, pelvic and breast exam

  • DEXA at 65: All women 65 and older, Grade B. Central DEXA of hip and spine. T-score -2.5 or lower is osteoporosis, -1.0 to -2.5 is low bone mass.
  • Repeat DEXA: interval by baseline T-score and risk, commonly 1 to 2 years after starting treatment, longer if normal and low risk.
  • Pelvic exam: not a screening tool in asymptomatic, nonpregnant adults. Do it for symptoms: bleeding, discharge, pain, prolapse, or a mass.
  • Breast exam: clinical breast exam has insufficient evidence as an added screen. Teach awareness of changes, rely on mammography for screening, evaluate any lump diagnostically with imaging regardless of a recent normal mammogram.
  • Postmenopausal bleeding: never normal. Needs same-visit triage and endometrial evaluation.
  • Ovarian cancer screening: do NOT order CA-125 or transvaginal ultrasound to screen asymptomatic average-risk women. Grade D.

5. Shared screenings - exact ages and intervals

Both patients, unless a sex-specific rule in Sections 3 or 4 overrides it.

ScreeningWho and whenInterval / stopGrade
Blood pressureAll adults 18 and olderAt every visit, at least annually. Confirm high readings out of officeA
Colorectal cancerAll adults 45 to 75Colonoscopy every 10 years, OR FIT annually, OR stool DNA-FIT every 1 to 3 years, OR CT colonography or flex sig every 5 years. Age 76 to 85: selective, Grade C. Over 85: do not screen, Grade D.A for 50-75, B for 45-49
Lung cancer - low-dose CTAdults 50 to 80 with 20 pack-year or more history who smoke now OR quit within the last 15 yearsAnnual LDCT. Stop once quit for 15 years, or a health problem substantially limits life expectancy or ability to have lung surgeryB
Diabetes / prediabetesAdults 35 to 70 with overweight or obesityEvery 3 years with A1C, fasting glucose, or OGTTB
Lipids and statinStatin for primary prevention: 40 to 75 with CV risk factor(s) and 10-year risk 10% or higherLipid panel as needed for risk calculation. 7.5 to 10% risk is Grade CB / C
Hepatitis CAll adults 18 to 79Once. More often only with ongoing riskB
HIVAll persons 15 to 65 at least onceRepeat by risk. Over 65, screen if at increased riskA
DepressionAll adults, including older adultsPHQ-2 / PHQ-9, periodically and when indicatedB
Unhealthy alcohol useAll adults in primary careAUDIT-C or single-question screen, with brief counseling if positiveB
Tobacco useAll adultsAsk at every visit, advise, assess, assist, arrange. Pharmacotherapy plus counselingA
Unhealthy diet, activity, obesityAdults with high BMI or CV riskBehavioral counseling interventions, Grade B in those groupsB
Falls prevention - exerciseCommunity-dwelling adults 65 and older at increased fall riskExercise or physical therapy intervention. Multifactorial assessment is Grade C, selectiveB
Syphilis, STIs, Hep BPersons at increased risk only at this ageRisk-based, not universal at 65. Hep B screening Grade B if at increased riskA / B by infection
Latent TBPersons at increased risk (born or lived in high-prevalence country, congregate settings)Once if at risk and never testedB
Pack-year math, done once and done right: Packs per day multiplied by years smoked. 1 pack a day for 20 years is 20 pack-years. Half a pack a day for 40 years is also 20 pack-years. Both qualify for lung screening if the age and quit-time rules are also met.

6. Immunizations for a healthy 65-year-old

Identical for male and female. Based on the CDC Adult Immunization Schedule 2025 and ACIP updates adopted through June 2025. Always confirm a prior record before ordering, and use the state immunization registry when history is unclear.

Influenza - every year

Annual, 1 dose

  • Dose: 1 dose every fall, every year.
  • For 65 and older, CDC preferentially recommends a higher-dose or adjuvanted product over standard-dose unadjuvanted vaccine: high-dose inactivated (HD-IIV3), recombinant (RIV3), or adjuvanted inactivated (aIIV3). If none is available, give any age-appropriate influenza vaccine, do not delay.
  • Never at this age: live attenuated influenza vaccine (LAIV, nasal spray) is not approved for age 50 and older.
  • Timing: September to October is ideal, continue while influenza circulates.

COVID-19 - stay up to date

2 or more doses of 2024-2025 vaccine at 65+

  • CDC 2025 schedule, age 65 and older: 2 or more doses of the 2024-2025 COVID-19 vaccine, per the schedule notes for prior vaccination status.
  • Second dose timing: adults 65 and older receive a second dose of the 2024-2025 vaccine 6 months after the previous dose.
  • Unvaccinated older adults need the initial series for the current formulation as directed in the CDC notes, followed by that additional dose. Do not restart a series because an interval was long.
  • Can be coadministered with influenza and most other vaccines at different anatomic sites.

Tdap, then Td or Tdap

Once, then every 10 years

  • If never had Tdap: 1 dose of Tdap now, regardless of when the last Td was.
  • Then: Td or Tdap booster every 10 years for life.
  • Wound care: Tdap or Td by wound type and history, plus tetanus immune globulin for severe or dirty wounds if history is inadequate.
  • Tdap is also recommended in each pregnancy, which does not apply to this patient, but is a common distractor.

Recombinant zoster - Shingrix (RZV)

2 doses, age 50 and older

  • Dose and series: 2 doses, 2 to 6 months apart. If the second dose is late, do not restart, just give it.
  • Give it even if: he or she had shingles before, had chickenpox, or received the old live zoster vaccine (ZVL). Wait until an acute shingles episode has resolved.
  • RZV is recombinant, not live. It is also recommended from age 19 for immunocompromised adults, with a 1 to 2 month interval option in that group.
  • Counsel: sore arm, fatigue, myalgia, and fever for 1 to 3 days are common. Plan the timing around important events.

Pneumococcal - age threshold is now 50

1 dose of PCV at 65 if PCV-naive

  • The change: On October 23, 2024, CDC lowered the routine age-based pneumococcal recommendation from 65 to 50. A healthy 65-year-old who never had it is already 15 years overdue, not newly eligible.
  • For a PCV-naive adult 50 and older, any ONE of these satisfies it: a single dose of PCV20 alone, OR a single dose of PCV21 alone, OR PCV15 followed by PPSV23.
  • If PCV15 is used: PPSV23 follows at least 1 year later. Minimum interval is 8 weeks only for immunocompromise, cochlear implant, or CSF leak.
  • If PCV20 or PCV21 is used: no PPSV23 is needed. The series is complete with that one dose.
  • If he or she already had PPSV23 or PCV13 in the past: use the CDC PneumoRecs VaxAdvisor logic for that specific history. Do not guess. In general, a PCV20 or PCV21 dose at least 5 years after a prior PPSV23 at 65 or older, or at least 1 year after PPSV23 before 65, is the pattern the schedule uses.

RSV - read this one exactly

Not routine for a healthy 65-year-old

  • Current CDC rule (April 2025 ACIP vote, adopted June 25, 2025): a single dose of RSV vaccine for ALL adults age 75 and older, AND for adults age 50 to 74 who are at increased risk for severe RSV disease.
  • What that means at 65: a healthy 65-year-old with no risk factors is NOT recommended to get RSV vaccine now. Offer it at 65 only if a risk factor is present. Otherwise, wait until 75 or until a risk factor develops.
  • Increased risk includes: chronic heart or lung disease, immunocompromise, diabetes with end-organ damage, advanced kidney or liver disease, frailty, neurologic conditions, and residence in a nursing home or long-term care facility, among CDC-listed factors.
  • Products: Arexvy, Abrysvo, or mResvia. CDC expresses no preference among them for older adults. Single dose only, it is not annual. If already received one dose, do not give another at this time.
  • Best timing: late summer to early fall, before RSV season.
  • History trap: the old rule, adults 60 and older may receive it using shared clinical decision making, was replaced in June 2024. Do not answer with shared clinical decision making for RSV on a current exam.

Also check at 65 - risk-based, not automatic

  • Hepatitis B: universally recommended for adults younger than 60. At 60 and older, vaccinate if a risk factor is present (diabetes with clinician decision, household or sexual contacts, healthcare work, travel, liver disease, injection drug use, incarceration, dialysis) and offer to others who want protection per shared decision. Series is 2 or 3 doses by product.
  • Hepatitis A: risk-based only (travel, liver disease, exposure risk, homelessness, drug use).
  • MMR and varicella: only if no evidence of immunity and a risk indication, for example healthcare personnel or an outbreak. Born before 1957 is generally considered presumptive evidence of measles and mumps immunity for routine purposes, with healthcare exceptions. Both are LIVE vaccines, see traps below.
  • HPV: routine through age 26, shared clinical decision making age 27 to 45, NOT recommended over 45. Do not start it at 65.
  • Meningococcal: risk-based only (asplenia, complement deficiency, outbreak, travel).

Catch-up table - unknown vaccine history at 65

Rule for unknown history: treat as unvaccinated for that antigen, document the attempt to obtain records, check the registry, and start. Extra doses of most vaccines are safer than leaving an older adult unprotected. Serology is only useful for selected antigens, such as hepatitis B in healthcare workers.

VaccineIf history is unknown
InfluenzaGive this season's dose now, prefer HD-IIV3, RIV3, or aIIV3
COVID-19Treat as unvaccinated for the current formulation and follow the CDC notes for unvaccinated adults 65 and older, including the additional dose 6 months later
Tdap / TdGive Tdap now, then Td or Tdap in 10 years. For a completely unknown tetanus history, use the 3-dose primary series: Tdap, then Td at least 4 weeks later, then Td 6 to 12 months after that
RZV (Shingrix)Give dose 1 now, dose 2 in 2 to 6 months
PneumococcalGive 1 dose PCV20 or PCV21 now and be done, or PCV15 now plus PPSV23 in at least 1 year
RSVGive 1 dose ONLY if age 75 or older, or age 50 to 74 with a CDC risk factor. Unknown history alone does not make a healthy 65-year-old eligible
Hepatitis BAssess risk, offer or recommend by risk and shared decision at this age, start the product-specific series if accepted
Classic vaccine traps:
1. Live vaccines: MMR, varicella, and LAIV are live. Avoid live vaccines in significant immunocompromise and in pregnancy, and separate two live vaccines by at least 28 days if not given on the same day. RZV, RSV, PCV, influenza inactivated, Tdap, and COVID-19 vaccines are NOT live.
2. Zoster before 50: RZV is routine at 50, not before, except from age 19 if immunocompromised. Do not give it to a healthy 40-year-old.
3. Spacing: inactivated and recombinant vaccines can generally be given at any interval and coadministered. The 4-day grace period applies to most minimum intervals, but not to the 28-day live vaccine rule or rabies.
4. Do not restart series for a late second dose of Shingrix or a late PPSV23 after PCV15. Give the missing dose.
5. PCV20 or PCV21 plus PPSV23 is a wasted dose in a PCV-naive older adult. PPSV23 only follows PCV15 in the routine older adult pathway.
6. RSV is one dose, not annual, and not shared clinical decision making under current rules.

7. Medicare framing - Welcome vs Annual Wellness

Workshop cases love this distinction because patients call all three a physical, and only two are Medicare benefits.

Welcome to Medicare Visit (IPPE)Annual Wellness Visit (AWV)Routine annual physical
WhenOnce only, within the first 12 months of Part B enrollment. Miss the window and it is gone.Once every 12 months, after Part B for more than 12 months. First AWV cannot be within 12 months of the IPPE or of Part B start.Any time, but it is not a Medicare benefit.
Cost to patient$0 for the visit itself if the provider accepts assignment, Part B deductible does not apply.$0 for the visit itself if the provider accepts assignment.Patient pays, unless a Medicare Advantage plan adds it as a supplemental benefit.
What it isReview of medical and social history, BP, vision screen, BMI, depression and safety screening, a screening ECG only if referred from this visit and only under its own rules, end-of-life planning on request, and a written screening and vaccine plan.Health Risk Assessment, updated history and provider list, cognitive impairment check, updated screening schedule, risk factor review, and a personalized prevention plan. Subsequent visits update the plan.Head-to-toe examination and routine labs as the clinician chooses.
What it is NOTNeither Medicare visit is a comprehensive head-to-toe physical exam. Neither includes routine labs or treatment of new or chronic problems for free. If problem-focused care or extra tests happen at the same appointment, those are billed separately and Part B deductible and 20 percent coinsurance can apply. Tell the patient that in advance.Not covered by Original Medicare.
Exam pearlAt exactly 65, a newly enrolled patient is usually in the Welcome window. The correct answer is often IPPE now, first AWV at least 12 months later, with vaccines and USPSTF screenings ordered under their own preventive benefits, not because the wellness visit itself covers the test.Do not document an AWV as a physical.

8. Stop, or do not start, list

Questions test the stops as hard as the starts. If a vignette patient is 65, check this list before ordering anything.

Stops at or before 65

  • Cervical cancer screening: stop at 65 with adequate prior screening and no CIN 2 or higher in 20 years. See Section 4 for the exact definition.
  • HPV vaccination: do not start over 45. Shared decision only applied at 27 to 45.
  • Anxiety screening as a USPSTF B: the B grade ends at 64. At 65, use clinical judgment.
  • HIV universal window ends at 65: Grade A is 15 to 65. After that, risk-based testing continues.

Do not order routinely at any older age

  • Prostate PSA at 70 and older: Grade D. At 65 it is shared decision, never automatic.
  • Colorectal screening over 85: Grade D. Age 76 to 85 is selective, Grade C.
  • Ovarian screening (CA-125, ultrasound): Grade D in asymptomatic women.
  • Testicular screening: Grade D in asymptomatic males.
  • Asymptomatic bacteriuria screening: Grade D in nonpregnant adults. Do not treat a positive dipstick without symptoms.
  • Aspirin to START for primary prevention at 60 and older: Grade D. Bleeding risk outweighs benefit. This does not mean stop aspirin used for secondary prevention.
  • Vitamin D to prevent falls: Grade D. Exercise is the B-grade intervention.
  • Routine screening ECG, carotid stenosis ultrasound, and COPD spirometry in asymptomatic adults: Grade D for ECG in low-risk asymptomatic adults and carotid screening, I or D patterns that all point the same way, do not screen without symptoms or risk indication.
Coming stops to anticipate, not yet stopped at 65: Mammography evidence becomes insufficient after 74, diabetes screening Grade B ends at 70, lung LDCT ends at 80 or 15 years after quitting, AAA window ends at 75, colorectal routine screening ends at 75. At 65, all of those are still active decisions.

9. Study tools

Tap a flashcard to flip it. Work the cases before opening the answers. Then take the quiz.

Flashcards - high-yield facts

Case vignettes

Case 1 - 65-year-old male, smoker

Mr. D, 65, presents for his first visit after enrolling in Medicare 3 months ago. He smoked 1.5 packs a day for 30 years and still smokes. He quit for 2 months last year, then restarted. BP 148/86, BMI 29. No prior colonoscopy, no pneumococcal or zoster vaccine on record, last tetanus shot unknown, last flu shot 3 years ago. He asks for a PSA because his brother had prostate cancer at 68. No urinary symptoms. He reports trouble getting an erection for the past year.

Work it: What visit type, what screenings, what vaccines, what conversations?

Answer: This is a Welcome to Medicare visit (IPPE), he is within 12 months of Part B. Screenings due: colorectal screening (any USPSTF option, colonoscopy is reasonable given never screened), annual lung LDCT (age 50 to 80, pack-years are 1.5 x 30 = 45, well over 20, currently smoking), one-time AAA ultrasound (man 65 to 75, ever smoked), BP management and lipids with a statin risk calculation, A1C (age 35 to 70 with overweight), one-time hepatitis C, HIV if never tested, depression screening, alcohol and tobacco counseling with pharmacotherapy offered. PSA: shared decision making, Grade C at 65, discuss family history as a risk factor, benefits and harms, and document his informed choice, do not just order it. ED: evaluate as a cardiovascular flag, check A1C, lipids, BP, meds, and counsel that smoking contributes. Vaccines: influenza with a preferred 65 and older formulation, COVID-19 per the 65 and older schedule, Tdap now (history unknown) then Td or Tdap every 10 years, RZV dose 1 now and dose 2 in 2 to 6 months, pneumococcal with 1 dose PCV20 or PCV21 (or PCV15 plus PPSV23 in 1 year). RSV: he has a risk argument only if a CDC risk factor is present, smoking alone with chronic lung disease would count through that lung disease, but age 65 alone does not. Document a falls, cognition, function, and Beers review, and set the first Annual Wellness Visit at least 12 months after this visit.

Case 2 - 65-year-old female, well woman

Mrs. L, 65, is due for a comprehensive exam. Last mammogram was 3 years ago. Pap history: HPV co-tests negative at age 57 and 62, no history of CIN 2 or higher, cervix intact. She has never had a DEXA. BMI 24, never smoked, walks daily, no falls. Vaccine record shows Tdap 8 years ago, Shingrix dose 1 given 8 months ago, no pneumococcal vaccine, flu shot last fall.

Work it: What is due, what is finished, and what is the one vaccine catch-up error to avoid?

Answer: Due now: mammography (biennial 40 to 74, she is 3 years out, so overdue), DEXA (all women at 65), colorectal screening if not current (routine to 75), BP, lipids and statin risk review, depression screening, hepatitis C once if never done. Diabetes screening Grade B does not automatically apply because BMI is 24 and she is not in the overweight or obesity group, use clinical judgment. Cervical screening: STOP. She has adequate prior screening (2 negative co-tests within 10 years, most recent within 5 years, ages 57 and 62 at presentation age 65 fits the look-back as documented in the vignette history, no CIN 2 or higher), so no Pap today, and that stop should be explained and documented. Vaccines: pneumococcal now (PCV20 or PCV21 alone, or PCV15 plus PPSV23 in 1 year), influenza this fall with a preferred formulation, COVID-19 up to date for 65 and older, Td or Tdap booster in 2 years (10 years after her Tdap). Shingrix: give dose 2 NOW. It is late, at 8 months, but the rule is do not restart the series, just give the missing dose. RSV: healthy, never smoked, no CDC risk factor, so not recommended at 65, revisit at 75 or if a risk factor develops. No AAA ultrasound, no ovarian screening, no screening pelvic exam without symptoms.

Quiz - tap an answer for the rationale

One-page cheat sheet - bring to workshop

At 65, BOTH: BP every visit - Colorectal 45 to 75 - LDCT if 50 to 80, 20+ pack-years, quit under 15 years, annually - A1C if 35 to 70 and overweight or obese, every 3 years - Lipids and statin risk - Hep C once, 18 to 79 - HIV once, 15 to 65 - Depression screen - Alcohol and tobacco counseling - Falls: exercise if at risk.

MALE only: AAA ultrasound once, 65 to 75, ever smoked - PSA is a conversation at 55 to 69, never screen 70 and older - ED equals CV risk check.

FEMALE only: Mammogram every 2 years, 40 to 74 - DEXA at 65 - Cervical STOPS at 65 if adequate prior screening and no CIN 2+ in 20 years - No ovarian screening, no routine pelvic screening exam.

VACCINES at 65: Flu yearly, prefer high-dose, recombinant, or adjuvanted - COVID up to date, 65 and older get an additional dose 6 months after the prior 2024-2025 dose - Tdap once, then Td or Tdap every 10 years - Shingrix 2 doses, 2 to 6 months apart, age 50 and older - Pneumococcal at 50 and older now: PCV20 or PCV21 x 1, OR PCV15 then PPSV23 in 1 year - RSV: all 75 and older, plus 50 to 74 with risk only, 1 dose, not annual, not shared decision making anymore.

VISIT CHECKLIST: Med rec + Beers review - Vitals + BMI - Cognition - PHQ-2/9 - Falls + gait - ADLs / IADLs - Vision + hearing - Social drivers - Advance directive - Vaccine record from registry - Screening dates verified - Written prevention plan with next due dates - Medicare visit type documented correctly (IPPE vs AWV, neither is a physical).

NEVER / STOP: No Pap after 65 if adequate - No PSA at 70+ - No colorectal over 85 - No aspirin started for primary prevention at 60+ - No CA-125, no testicular screening, no asymptomatic bacteriuria screening, no vitamin D for fall prevention.